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13491-42-4

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13491-42-4 Structure

13491-42-4 Structure
IdentificationBack Directory
[Name]

2(1H)-Pyrimidinone, 1-b-D-arabinofuranosyl-4-(methylamino)-
[CAS]

13491-42-4
[Synonyms]

N4-Methylarabinocytidine
1-(b-D-arabinofuranosyl)-N4-methylcytosine
2(1H)-Pyrimidinone, 1-b-D-arabinofuranosyl-4-(methylamino)-
[Molecular Formula]

C10H15N3O5
[MDL Number]

MFCD30748938
[MOL File]

13491-42-4.mol
[Molecular Weight]

257.243
Chemical PropertiesBack Directory
[Melting point ]

257-260 °C
[Boiling point ]

504.2±60.0 °C(Predicted)
[density ]

1.69±0.1 g/cm3(Predicted)
[pka]

13.48±0.70(Predicted)
Hazard InformationBack Directory
[Uses]

N4-Methylarabinocytidine is a cytidine nucleoside analog. Cytidine analogs have a mechanism of inhibiting DNA methyltransferases (such as Zebularine, HY-13420), and have potential anti-metabolic and anti-tumor activities[1].
[References]

[1] Gowher H, et al. Mechanism of inhibition of DNA methyltransferases by cytidine analogs in cancer therapy. Cancer Biol Ther. 2004 Nov;3(11):1062-8. DOI:10.4161/cbt.3.11.1308
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