| Identification | Back Directory | [Name]
N-[6-(2,5-Dihydro-2,5-dioxo-1H-pyrrol-1-yl)-1-oxohexyl]-L-valyl-N5-(aminocarbonyl)-N-[4-[[[(4-nitrophenoxy)carbonyl]oxy]methyl]phenyl]-D-ornithinamide | [CAS]
1350456-66-4 | [Synonyms]
N-[6-(2,5-Dihydro-2,5-dioxo-1H-pyrrol-1-yl)-1-oxohexyl]-L-valyl-N5-(aminocarbonyl)-N-[4-[[[(4-nitrophenoxy)carbonyl]oxy]methyl]phenyl]-D-ornithinamide | [Molecular Formula]
C35H43N7O11 | [MOL File]
1350456-66-4.mol | [Molecular Weight]
737.76 |
| Chemical Properties | Back Directory | [Boiling point ]
1034.5±65.0 °C(Predicted) | [density ]
1.338±0.06 g/cm3(Temp: 20 °C; Press: 760 Torr)(Predicted) | [pka]
13.24±0.70(Predicted) |
| Hazard Information | Back Directory | [Uses]
MC-Val-D-Cit-PAB-PNP is a cleavable peptide linker molecule used in the synthesis of antibody-drug conjugates (ADCs). MC-Val-D-Cit-PAB-PNP contains a maleimidocaproyl (Mc) group that can be conjugated to an antibody and a p-nitrophenol (PNP) group that allows the peptide to be linked to antitumor compounds. | [IC 50]
Protease Cleavable Linker |
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ChemOrigin Pharm
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chemorigin.com/ |
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