| Identification | Back Directory | [Name]
T338C Src-IN-1 | [CAS]
1351926-90-3 | [Synonyms]
CS-2101
T338C Src-IN-1
T-338C Src-IN-1,T338C SrcIN1,T338C Src IN 1
Ethenesulfonamide, N-[3-[[4-amino-1-(1-methylethyl)-1H-pyrazolo[3,4-d]pyrimidin-3-yl]methyl]phenyl]- | [Molecular Formula]
C17H20N6O2S | [MDL Number]
MFCD28963987 | [MOL File]
1351926-90-3.mol | [Molecular Weight]
372.44 |
| Chemical Properties | Back Directory | [Boiling point ]
584.4±60.0 °C(Predicted) | [density ]
1.40±0.1 g/cm3(Predicted) | [storage temp. ]
Store at -20°C | [solubility ]
Soluble in DMSO | [pka]
7.96±0.50(Predicted) |
| Hazard Information | Back Directory | [Uses]
T338C Src-IN-1 is a potent mutant-Src T338C inhibitor; exhibited the most potent inhibition of T338C(IC50=111 nM) relative to WT c-Src (10-fold increase). | [References]
[1] Garske AL, et al. Chemical genetic strategy for targeting protein kinases based on covalent complementarity. Proc Natl Acad Sci U S A. 2011 Sep 13;108(37):15046-52. DOI:10.1073/pnas.1111239108 |
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Cckinase, Inc.
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BOC Sciences
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Biorbyt Ltd.
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