| Identification | Back Directory | [Name]
T338C Src-IN-2 | [CAS]
1351927-00-8 | [Synonyms]
T338C Src-IN-2
1-(3-((4-amino-1-isopropyl-1H-pyrazolo[3,4-d]pyrimidin-3-yl)methyl)phenyl)-2-fluoroethanone
Ethanone, 1-[3-[[4-amino-1-(1-methylethyl)-1H-pyrazolo[3,4-d]pyrimidin-3-yl]methyl]phenyl]-2-fluoro- | [Molecular Formula]
C17H18FN5O | [MDL Number]
MFCD28963988 | [MOL File]
1351927-00-8.mol | [Molecular Weight]
327.36 |
| Chemical Properties | Back Directory | [Boiling point ]
540.6±50.0 °C(Predicted) | [density ]
1.35±0.1 g/cm3(Predicted) | [storage temp. ]
Store at -20°C | [solubility ]
Soluble in DMSO | [pka]
4.31±0.30(Predicted) |
| Hazard Information | Back Directory | [Uses]
T338C Src-IN-2 is a potent mutant c-Src T338C kinase inhibitor with IC50 of 317 nM; also inhibits T338C/V323A and T338C/V323S with IC50 of 57 nM/19 nM. | [References]
[1] Garske AL, et al. Chemical genetic strategy for targeting protein kinases based on covalent complementarity. Proc Natl Acad Sci U S A. 2011 Sep 13;108(37):15046-52. DOI:10.1073/pnas.1111239108 |
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| Company Name: |
Musechem
|
| Tel: |
+1-800-259-7612 |
| Website: |
www.musechem.com |
| Company Name: |
Cckinase, Inc.
|
| Tel: |
+1 (732)236-3202 |
| Website: |
www.cckinase.com |
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