| Identification | Back Directory | [Name]
N-METHYLATED POMALIDOMIDE | [CAS]
1352827-50-9 | [Synonyms]
N-METHYLATED POMALIDOMIDE
N-Methylated pomalidomide >=98%
4-Amino-2-(1-methyl-2,6-dioxopiperidin-3-yl)isoindoline-1,3-dione
4-amino-2-(1-methyl-2,6-dioxopiperidin-3-yl)-2,3-d ihydro-1H-isoindole-1,3-dione | [Molecular Formula]
C14H13N3O4 | [MDL Number]
MFCD31703382 | [MOL File]
1352827-50-9.mol | [Molecular Weight]
287.27 |
| Chemical Properties | Back Directory | [Boiling point ]
544.3±45.0 °C(Predicted) | [density ]
1.519±0.06 g/cm3(Predicted) | [storage temp. ]
2-8°C | [solubility ]
Soluble to 100 mM in DMSO | [form ]
powder or crystals | [pka]
-0.80±0.20(Predicted) | [InChI]
1S/C14H13N3O4/c1-16-10(18)6-5-9(13(16)20)17-12(19)7-3-2-4-8(15)11(7)14(17)21/h2-4,9H,5-6,15H2,1H3 | [InChIKey]
YSWQOCGODHPKED-UHFFFAOYSA-N | [SMILES]
O=C(C(CC1)N(C2=O)C(C3=C2C=CC=C3N)=O)N(C)C1=O |
| Hazard Information | Back Directory | [Uses]
N-Methylated pomalidomide is a ligand used as a negative control for pomalidomide (P0018) in the recruitment of the Cereblon (CRBN) protein for targeted protein degradation and PROTAC (proteolysis-targeting chimeras) technology. | [reaction suitability]
reagent type: ligand | [storage]
Store at -20°C |
|
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Sigma-Aldrich
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Energy Chemical
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http://www.energy-chemical.com |
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