ChemicalBook--->CAS DataBase List--->135293-13-9

135293-13-9

135293-13-9 Structure

135293-13-9 Structure
IdentificationBack Directory
[Name]

2'-O-RHAMNOSYLICARISIDE II
[CAS]

135293-13-9
[Synonyms]

2'-O-rhaMnosylicariside Ⅱ
2"-O-rhamnosyl icariside I
2'-O-RHAMNOSYLICARISIDE II
2-(Hydroxymethyl)-4-[(1R)-1-hydroxy-2-{[6-(4-phenylbutoxy)hexyl]a mino}ethyl]phenol
4H-1-Benzopyran-4-one, 3-[[6-deoxy-2-O-(6-deoxy-α-L-mannopyranosyl)-α-L-mannopyranosyl]oxy]-5,7-dihydroxy-2-(4-methoxyphenyl)-8-(3-methyl-2-buten-1-yl)-
[EINECS(EC#)]

2017-001-1
[Molecular Formula]

C33H40O14
[MDL Number]

MFCD04039816
[MOL File]

135293-13-9.mol
[Molecular Weight]

660.66
Chemical PropertiesBack Directory
[Boiling point ]

892.8±65.0 °C(Predicted)
[density ]

1.50±0.1 g/cm3 (20 ºC 760 Torr)
[solubility ]

DMSO: Soluble
[form ]

Solid
[pka]

6.29±0.40(Predicted)
[color ]

Light yellow to yellow
Safety DataBack Directory
[Symbol(GHS) ]

Exclamation Mark (GHS07)
GHS07
[Signal word ]

Warning
[Hazard statements ]

H302-H315-H319-H335
[Precautionary statements ]

P261-P305+P351+P338
Hazard InformationBack Directory
[Description]

2”-O-Rhamnosylicariside II (2”-O-Rhys II) is a flavonoid glycoside that has been found in Epimedium and has hepatotoxic activity.1,2 It increases aspartate aminotransferase (AST), lactate dehydrogenase (LDH), and malondialdehyde (MDA) levels, as well as decreases glutathione (GSH) levels in Hl 7702 cells when used at a concentration of 66 µg/ml. 2’-O-Rhys II (100 µM) induces 100% mortality in zebrafish larvae.2 It also induces hepatocellular vacuolization and degeneration in adult zebrafish when used at a concentration of 25 µM.WARNING This product is not for human or veterinary use.
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