| Identification | Back Directory | [Name]
CRABP-II ligand 1 | [CAS]
135325-47-2 | [Synonyms]
ATRA-hydroxyimino
CRABP-II ligand 1
Retinoic acid, 4-(hydroxyimino)- (9CI) | [Molecular Formula]
C20H27NO3 | [MDL Number]
MFCD32062704 | [MOL File]
135325-47-2.mol | [Molecular Weight]
329.43 |
| Hazard Information | Back Directory | [Uses]
ATRA-hydroxyimino (CRABP-II ligand 1), the Retinoic acid (ATRA)-based moiety, binds to cIAP1 ligand (Bestatin) via a linker to form SNIPER to degrade CRABP-II in IMR-32 cells[1]. | [References]
[1] Scheepstra M, et al. Bivalent Ligands for Protein Degradation in Drug Discovery. Comput Struct Biotechnol J. 2019 Jan 25;17:160-176. DOI:10.1016/j.csbj.2019.01.006 |
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