ChemicalBook--->CAS DataBase List--->1353676-65-9

1353676-65-9

1353676-65-9 Structure

1353676-65-9 Structure
IdentificationBack Directory
[Name]

5,7,3',4'-Tetrahydroxy- 3-Methoxy-8,5'-diprenylflavone
[CAS]

1353676-65-9
[Synonyms]

-diprenylflavone
5,7,3',4'-Tetrahydroxy-3-methoxy-8,5'-diprenylflavone
5,7,3',4'-Tetrahydroxy- 3-Methoxy-8,5'-diprenylflavone
2-[3,4-dihydroxy-5-(3-methylbut-2-enyl)phenyl]-5,7-dihydroxy-3-methoxy-8-(3-methylbut-2-enyl)chromen-4-one
2-[3,4-Dihydroxy-5-(3-methyl-2-buten-1-yl)phenyl]-5,7-dihydroxy-3-methoxy-8-(3-methyl-2-buten-1-yl)-4H-1-benzopyran-4-one
4H-1-Benzopyran-4-one, 2-[3,4-dihydroxy-5-(3-methyl-2-buten-1-yl)phenyl]-5,7-dihydroxy-3-methoxy-8-(3-methyl-2-buten-1-yl)-
[Molecular Formula]

C26H28O7
[MOL File]

1353676-65-9.mol
[Molecular Weight]

452.5
Chemical PropertiesBack Directory
[Boiling point ]

694.1±55.0 °C(Predicted)
[density ]

1.35±0.1 g/cm3(Predicted)
[pka]

6.42±0.40(Predicted)
Hazard InformationBack Directory
[Uses]

5,7,3',4'-Tetrahydroxy-3-methoxy-8,5'-diprenylflavone is a natural product that can be extracted from B. papyrifera. 5,7,3',4'-Tetrahydroxy-3-methoxy-8,5'-diprenylflavone has potent anti-proliferation effects on ER-positive breast cancer cells, with an IC50 value of 4.41 μM for MCF-7 cells. 5,7,3',4'-Tetrahydroxy-3-methoxy-8,5'-diprenylflavone also reduces the tumor growth in the BCAP-37 xenograft[1].
[References]

[1] FujiangGuo, et al. Prenylflavone derivatives from Broussonetia papyrifera, inhibit the growth of breast cancer cells in vitro and in vivo. Phytochemistry Letters. Volume 6, Issue 3, August 2013, Pages 331-336.
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