| Identification | Back Directory | [Name]
clathrodin | [CAS]
135383-64-1 | [Synonyms]
clathrodin
1H-Pyrrole-2-carboxamide, N-[(2E)-3-(2-amino-1H-imidazol-4-yl)-2-propenyl]- (9CI) | [Molecular Formula]
C11H13N5O | [MOL File]
135383-64-1.mol | [Molecular Weight]
231.25 |
| Hazard Information | Back Directory | [Description]
Clathrodin is a natural modulator of voltage-gated sodium (NaV) channels. | [Uses]
Clathrodin is a marine alkaloid that can be isolated from sponges of the genus, Agelas. Clathrodin is a modulator of voltage-gated sodium (NaV) channels. Clathrodin is a sodium channel neurotoxin influencing sodium channel ionic conductance[1][2]. | [References]
[1] Rentas AL, et al. Effect of alkaloid toxins from tropical marine sponges on membrane sodium currents. Toxicon. 1995 Apr;33(4):491-7. DOI:10.1016/0041-0101(94)00164-4 |
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