| Hazard Information | Back Directory | [Description]
UNC0006 is a β-arrestin-biased dopamine D2 ligand for probing signal transduction pathways essential for antipsychotic efficacy. Elucidating the key signal transduction pathways essential for both antipsychotic efficacy and side-effect profiles is essential for developing safer and more effective therapies. Noncanonical modes of dopamine D(2) receptor (D(2)R) signaling via β-arrestins are important for the therapeutic actions of both antipsychotic and antimanic agents | [Uses]
UNC0006 is a β-arrestin-biased dopamine D2 ligand. UNC0006 can be used in the study of antipsychotic[1]. | [References]
[1] Allen J A, et al. Discovery of β-arrestin–biased dopamine D2 ligands for probing signal transduction pathways essential for antipsychotic efficacy[J]. Proceedings of the National Academy of Sciences, 2011, 108(45): 18488-18493. |
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| Company Name: |
InvivoChem
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| Tel: |
13549236410 |
| Website: |
https://www.invivochem.cn/ |
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