| Identification | Back Directory | [Name]
5-(3-Azidopropyl)uridine | [CAS]
1354419-08-1 | [Synonyms]
5-(2-Azidoethyl)uridine
5-(3-Azidopropyl)uridine | [Molecular Formula]
C12H17N5O6 | [MDL Number]
MFCD32689950 | [MOL File]
1354419-08-1.mol | [Molecular Weight]
327.3 |
| Hazard Information | Back Directory | [Uses]
5-(3-Azidopropyl)uridine is a thymidine analog. Analogs of this series have insertional activity towards replicated DNA. They can be used to label cells and track DNA synthesis[1]. 5-(3-Azidopropyl)uridine is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups. | [References]
[1] Cavanagh BL, et al. Thymidine analogues for tracking DNA synthesis. Molecules. 2011 Sep 15;16(9):7980-93. DOI:10.3390/molecules16097980 |
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