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Avidinorubicin is a novel anthracycline with platelet aggregation inhibitory activity. | [Uses]
Avidinorubicin is an antimicrobial agent found in Streptomyces avidinii, exhibiting activity against both Gram-positive and Gram-negative bacteria. Additionally, Avidinorubicin inhibits thrombin (HY-114164)-induced platelet aggregation, with an IC50 of 7.9 μM[1]. | [References]
[1] Aoki M, et al. Structural studies on avidinorubicin, a novel anthracycline with platelet aggregation inhibitory activity. J Antibiot (Tokyo). 1991 Jun;44(6):635-45. DOI:10.7164/antibiotics.44.635
[2] Yang J, et al. Recent advances in chemical synthesis of amino sugars[J]. Molecules, 2023, 28(12): 4724. |
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