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135662-05-4

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135662-05-4 Structure

135662-05-4 Structure
IdentificationBack Directory
[Name]

DNP-PLAYWAR
[CAS]

135662-05-4
[Synonyms]

DNP-PLAYWAR
360 MMP FRET SUBSTRATE VI
MMP-8 SUBSTRATE, FLUOROGENIC
DNP-PRO-LEU-ALA-TYR-TRP-ALA-ARG
NEUTROPHIL COLLAGENASE SUBSTRATE
DNP-PRO-LEU-ALA-TYR-TRP-ALA-ARG-OH
MMP-8/MMP-26 Fluorogenic Substrate
MMP-8 Substrate, Fluorogenic、FRET Substrate
MMP-8 Substrate, Fluorogenic (Neutrophil Collagenase Substrate)
Matrix Metalloproteinase-8/Matrix Metalloproteinase-26 Fluorogenic Substrate
L-Arginine, 1-(2,4-dinitrophenyl)-L-prolyl-L-leucyl-L-alanyl-L-tyrosyl-L-tryptophyl-L-alanyl-
DNP-PLAYWAR;DNP-PRO-LEU-ALA-TYR-TRP-ALA-ARG-OH;MATRIX METALLOPROTEINASE-8/MATRIX METALLOPROTEINASE-26 FLUOROGENIC SUBSTRATE;MMP-8/MMP-26 FLUOROGENIC SUBSTRATE
[Molecular Formula]

C49H63N13O13
[MDL Number]

MFCD08459399
[MOL File]

135662-05-4.mol
[Molecular Weight]

1042.1
Chemical PropertiesBack Directory
[density ]

1.48±0.1 g/cm3(Predicted)
[storage temp. ]

-20°C
[pka]

3.34±0.10(Predicted)
[Sequence]

{DNP}-Pro-Leu-Ala-Tyr-Trp-Ala-Arg
Hazard InformationBack Directory
[Uses]

MMP-8/MMP-26 Fluorogenic substrate (DNP-Pro-Leu-Ala-Tyr-Trp-Ala-Arg) is a matrix metalloproteinase-8 (MMP-8) fluorogenic substrate. MMP-8/MMP-26 Fluorogenic substrate can be used for the research of atherosclerosis, pulmonary fibrosis, and sepsis[1].
[References]

[1] Morla S, et al. Discovery of Sulfated Small Molecule Inhibitors of Matrix Metalloproteinase-8. Biomolecules. 2020 Aug 9;10(8):1166. DOI:10.3390/biom10081166
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