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135702-23-7

135702-23-7 Structure

135702-23-7 Structure
IdentificationBack Directory
[Name]

AMYLIN (8-37) (HUMAN)
[CAS]

135702-23-7
[Synonyms]

Human amylin 8-37
AMYLIN (8-37) (HUMAN)
Amylin (8-37), amide, rat
AMYLIN FRAGMENT 8-37 HUMAN
amylin fragment 8-37 amide
AMYLIN (8-37) (HUMAN) USP/EP/BP
ATQRLANFLVHSSNNFGAILSSTNVGSNTY-NH2
diabetes associated peptide fragment 8-37 amide
Diabetes associated peptide fragment 8-37 amide, ≥97% (HPLC)
Ala-Thr-Gln-Arg-Leu-Ala-Asn-Phe-Leu-Val-His-Ser-Ser-Asn-Asn-Phe-Gly-Ala-Ile-Leu-Ser-Ser-Thr-Asn-Val-Gly-Ser-Asn-Thr-Tyr-NH2
H-ALA-THR-GLN-ARG-LEU-ALA-ASN-PHE-LEU-VAL-HIS-SER-SER-ASN-ASN-PHE-GLY-ALA-ILE-LEU-SER-SER-THR-ASN-VAL-GLY-SER-ASN-THR-TYR-NH2
Amylin (8-37) (human) trifluoroacetate salt H-Ala-Thr-Gln-Arg-Leu-Ala-Asn-Phe-Leu-Val-His-Ser-Ser-Asn-Asn-Phe-Gly-Ala-Ile-Leu-Ser-Ser-Thr-Asn-Val-Gly-Ser-Asn-Thr-Tyr-NH2 trifluoroacetate salt
LYS-CYS-ASN-THR-ALA-THR-CYS-ALA-THR-GLN-ARG-LEU-ALA-ASN-PHE-LEU-VAL-HIS-SER-SER-ASN-ASN-PHE-GLY-ALA-ILE-LEU-SER-SER-THR-ASN-VAL-GLY-SER-ASN-THR-TYR-NH2: KCNTATCATQRLANFLVHSSNNFGAILSSTNVGSNTY-NH2DISULFIDE BRIDGE CYS2-CYS7
L-Tyrosinamide, L-alanyl-L-threonyl-L-glutaminyl-L-arginyl-L-leucyl-L-alanyl-L-asparaginyl-L-phenylalanyl-L-leucyl-L-valyl-L-histidyl-L-seryl-L-seryl-L-asparaginyl-L-asparaginyl-L-phenylalanylglycyl-L-alanyl-L-isoleucyl-L-leucyl-L-seryl-L-seryl-L-threonyl-L-asparaginyl-L-valylglycyl-L-seryl-L-aspara...
L-Alanyl-L-threonyl-L-glutaminyl-L-arginyl-L-leucyl-L-alanyl-L-asparaginyl-L-phenylalanyl-L-leucyl-L-valyl-L-histidyl-L-seryl-L-seryl-L-asparaginyl-L-asparaginyl-L-phenylalanylglycyl-L-alanyl-L-isoleucyl-L-leucyl-L-seryl-L-seryl-L-threonyl-L-asparaginyl-L-valylglycyl-L-seryl-L-asparaginyl-L-threonyl-L-tyrosinamide
[Molecular Formula]

C138H216N42O45
[MDL Number]

MFCD00214583
[MOL File]

135702-23-7.mol
[Molecular Weight]

3183.45
Chemical PropertiesBack Directory
[density ]

1.51±0.1 g/cm3(Predicted)
[storage temp. ]

−20°C
[form ]

Solid
Safety DataBack Directory
[WGK Germany ]

3
Hazard InformationBack Directory
[Uses]

Amylin (8-37), human is a fragment of human Amylin. Amylin (8-37), human has direct vasodilator effects in the isolated mesenteric resistance artery of the rat. Human Amylin is a small hormone secreted by pancreatic β-cells that forms aggregates under insulin deficiency metabolic conditions, and it constitutes a pathological hallmark of type II diabetes mellitus[1].
[References]

[1] H C Champion, et al. Analysis of responses to hAmylin, hCGRP, and hADM in isolated resistance arteries from the mesenteric vascular bed of the rat. Peptides. 2001 Sep;22(9):1427-34. DOI:10.1016/s0196-9781(01)00482-x
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