| Identification | Back Directory | [Name]
(S)-N-(1-Azabicyclo[2.2.2]oct-3-yl)-5,6,7,8-tetrahydro-1-naphthalenecarboxamide | [CAS]
135729-78-1 | [Synonyms]
Palonosetron Impurity 3
Palonosetron Impurity 20
Palonosetron Impurity 27
Palonosetron Impurity 25
Palonosetron Impurity 1
Palonosetron Intermediate
(S)-N-(1-Azabicyclo[2.2.2]oct-3-yl)-5,6,7,8-tetra
(S)-N-(Quinuclidin-3-yl)-5,6,7,8-tetrahydronaphthalene-1-carboxaMide
N-(1-azabicyclo[2.2.2]octan-3-yl)-5,6,7,8-tetrahydronaphthalene-1-carboxamide
(S)-N-1-azabicyclo[2.2.0]oct-3-yl-5,6,7,8-tetrahydro-1-naphthalenecarboxamide
N-(3S)-1-Azabicyclo[2.2.2]oct-3-yl-5,6,7,8-tetrahydro-1-naphthalenecarboxaMide
(S)-N-(1-Azabicyclo[2.2.2]oct-3-yl)-5,6,7,8-tetrahydro-1-naphthalenecarboxamide
N-[(3S)-1-Azabicyclo[2.2.2]oct-3-yl] 5,6,7,8-tetrahydronaphthalene-1-carboxamide
1-Naphthalenecarboxamide, N-(3S)-1-azabicyclo[2.2.2]oct-3-yl-5,6,7,8-tetrahydro- | [Molecular Formula]
C18H24N2O | [MDL Number]
MFCD27923863 | [MOL File]
135729-78-1.mol | [Molecular Weight]
284.4 |
| Chemical Properties | Back Directory | [Melting point ]
157-159oC | [Boiling point ]
439.2±45.0 °C(Predicted) | [density ]
1.17 | [storage temp. ]
Refrigerator | [solubility ]
Chloroform (Slightly), Methanol (Slightly) | [form ]
Solid | [pka]
14.75±0.20(Predicted) | [color ]
White |
| Hazard Information | Back Directory | [Uses]
(S)-N-(1-Azabicyclo[2.2.2]oct-3-yl)-5,6,7,8-tetrahydro-1-naphthalenecarboxamide is an impurity in the synthesis of Palonosetron HCl (P165800), a serotonin 5-HT3 receptor antagonist used in the prevention and treatment of chemotherapy-induced nausea and vomiting (CINV). Antiemetic. |
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