| Identification | Back Directory | [Name]
FARNESYLTHIOACETIC ACID | [CAS]
135784-48-4 | [Synonyms]
FTA
FARNESYLTHIOACETIC ACID
S-FARNESYLTHIOACETIC ACID
WOQGETCAETYBTQ-OQLLNIDSSA-N
Farnesylthioacetic Acid (FTA)
(3,7,11,TRIMETHYL-2E,6E,10-DODECATRIENYL)THIOACETIC ACID
Acetic acid, 2-[[(2E,6E)-3,7,11-trimethyl-2,6,10-dodecatrien-1-yl]thio]- | [Molecular Formula]
C17H28O2S | [MDL Number]
MFCD00216146 | [MOL File]
135784-48-4.mol | [Molecular Weight]
296.47 |
| Hazard Information | Back Directory | [Description]
S-Farnesyl thioacetic acid is an analog of S-farnesyl cysteine which behaves as a competitive inhibitor of isoprenylated protein methyltransferase (also known as S-adenosylmethionine-dependent methyltransferase). It can also inhibit methylation of both farnesylated and geranylgeranylated substrates. | [Uses]
S-Farnesyl thioacetic acid is an analog of S-farnesyl cysteine, which is a prenylated protein methyltransferase (also known as S-adenosylmethionine-dependent methyltransferase) competitive inhibitors. It also inhibits the methylation of farnesylated and geranylgeranylated substrates. | [Definition]
ChEBI: 2-(3,7,11-trimethyldodeca-2,6,10-trienylthio)acetic acid is a sesquiterpenoid. | [storage]
Store at -20°C | [References]
[1] RANDO R R. Chemical biology of protein isoprenylation/methylation[J]. Biochimica et Biophysica Acta (BBA) - Lipids and Lipid Metabolism, 1996, 1300 1: Pages 5-16. DOI: 10.1016/0005-2760(95)00233-2 |
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| Company Name: |
Enzo Biochem Inc
|
| Tel: |
Enzo Biochem Inc. 13797054060 |
| Website: |
www.enzo.com |
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