| Identification | Back Directory | [Name]
L-PHENYLALANINE (3-13C) | [CAS]
136056-02-5 | [Synonyms]
L-PHENYLALANINE (3-13C)
L-PHENYLALANINE-BETA-13C
L-PHENYLALANINE-BETA-13C, 99 ATOM % 13C
(2S)-2-amino-3-phenyl(3^{13}C)propanoic acid | [Molecular Formula]
C9H11NO2 | [MDL Number]
MFCD00084040 | [MOL File]
136056-02-5.mol | [Molecular Weight]
166.2 |
| Chemical Properties | Back Directory | [Melting point ]
270-275 °C (dec.)(lit.) | [density ]
1.202±0.06 g/cm3(Temp: 25 °C; Press: 760 Torr)(predicted) | [form ]
Solid | [color ]
White to off-white | [Optical Rotation]
[α]25/D -33.0°, c = 1 in H2O | [InChI]
1S/C9H11NO2/c10-8(9(11)12)6-7-4-2-1-3-5-7/h1-5,8H,6,10H2,(H,11,12)/t8-/m0/s1/i6+1 | [InChIKey]
COLNVLDHVKWLRT-JCNVXSMLSA-N | [SMILES]
N[C@@H]([13CH2]c1ccccc1)C(O)=O |
| Hazard Information | Back Directory | [Uses]
L-Phenylalanine-3-13C is the 13C-labeled L-Phenylalanine. L-Phenylalanine ((S)-2-Amino-3-phenylpropionic acid) is an essential amino acid isolated from Escherichia coli. L-Phenylalanine is a α2δ subunit of voltage-dependent Ca+ channels antagonist with a Ki of 980 nM. L-phenylalanine is a competitive antagonist for the glycine- and glutamate-binding sites of N-methyl-D-aspartate receptors (NMDARs) (KB of 573 μM ) and non-NMDARs, respectively. L-Phenylalanine is widely used in the production of food flavors and pharmaceuticals[1][2][3][4]. | [IC 50]
NMDA Receptor | [References]
[1] Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216. DOI:10.1177/1060028018797110 |
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