| Identification | Back Directory | [Name]
Methanesulfonamide, N-[1'-[(2R)-6-cyano-1,2,3,4-tetrahydro-2-naphthalenyl]-3,4-dihydro-4-oxospiro[2H-1-benzopyran-2,4'-piperidin]-6-yl]- | [CAS]
136081-07-7 | [Synonyms]
Antiarrhythmic agent-1
Methanesulfonamide, N-[1'-[(2R)-6-cyano-1,2,3,4-tetrahydro-2-naphthalenyl]-3,4-dihydro-4-oxospiro[2H-1-benzopyran-2,4'-piperidin]-6-yl]- | [Molecular Formula]
C25H27N3O4S | [MOL File]
136081-07-7.mol | [Molecular Weight]
465.56 |
| Hazard Information | Back Directory | [Uses]
Antiarrhythmic agent-1 (example I) is an antiarrhythmic agent and an IKr potassium channel blocker (IC50<1 μM)[1]. | [References]
[1] Slaughter DE, et al. Preparation of N-[1'-(6-cyano-4-hydroxy-1,2,3,4-tetrahydro-2(R)-naphthalenyl-3,4-dihydro-4(R)-hydroxyspiro[2H-1-benzopyran-2,4'-piperidin-6-yl]methanesulfonamide as an antiarrhythmic agent.. World Intellectual Property Organization, WO9607411A1.1996-03-14. |
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