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1360823-60-4

1360823-60-4 Structure

1360823-60-4 Structure
IdentificationBack Directory
[Name]

gH625
[CAS]

1360823-60-4
[Synonyms]

gH625
[Molecular Formula]

C106H161N33O25
[MOL File]

1360823-60-4.mol
[Molecular Weight]

2297.62
Chemical PropertiesBack Directory
[density ]

1.46±0.1 g/cm3(Temp: 20 °C; Press: 760 Torr)(predicted)
[Sequence]

His-Gly-Leu-Ala-Ser-Thr-Leu-Thr-Arg-Trp-Ala-His-Tyr-Asn-Ala-Leu-Ile-Arg-Ala-Phe-NH2
Hazard InformationBack Directory
[Uses]

gH625 is a cell-penetrating viral peptide which is a part of glycoprotein H of Herpes simplex virus type I. gH625 is able to cross the cell membrane and to transport many conjugated cargoes into the cytosol. gH625 is permeable to the blood-brain barrier (BBB) and can enter the rat brain in vivo without toxic effects. gH625 can be used for siRNA delivery research[1].
[References]

[1] Singh T, et al. Versatility of cell-penetrating peptides for intracellular delivery of siRNA. Drug Deliv. 2018 Nov;25(1):1996-2006. DOI:10.1080/10717544.2018.1543366
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