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136098-04-9

136098-04-9 Structure

136098-04-9 Structure
IdentificationBack Directory
[Name]

ALPHA-DELTA-UA-2S-[1->4]-GLCN-6S SODIUM SALT
[CAS]

136098-04-9
[Synonyms]

α-δua-2s-[1→4]-glcn-6s
heparin disaccharide I-H sodium
HEPARIN DISACCHARIDE I-H SODIUM SALT
Heparin disaccharide I-H trisodium salt
ALPHA-DELTA-UA-2S-[1->4]-GLCN-6S SODIUM SALT
Heparin unsaturated disaccharide I-H, sodiuM salt
2-Amino-2-deoxy-4-O-(4-deoxy-2-O-sulfo-alpha-L-threo-hex-4-enopyranuronosyl)-D-glucose 6-(hydrogen sulfate) trisodium salt
trisodium:(2R,3R,4S)-2-[(2R,3S,4R,5R)-5-amino-4,6-dihydroxy-2-(sulfonatooxymethyl)oxan-3-yl]oxy-4-hydroxy-3-sulfonatooxy-3,4-dihydro-2H-pyran-6-carboxylate
[Molecular Formula]

C12H16NNa3O16S2
[MDL Number]

MFCD00466926
[MOL File]

136098-04-9.mol
[Molecular Weight]

563.35
Chemical PropertiesBack Directory
[storage temp. ]

−20°C
[form ]

solid
[color ]

white to faint yellow
[InChIKey]

WHYGSGRAJJCXLY-LXROVJCJSA-K
[SMILES]

[Na+].[Na+].[Na+].N[C@H]1C(O)O[C@H](COS([O-])(=O)=O)[C@@H](O[C@@H]2OC(=C[C@H](O)[C@H]2OS([O-])(=O)=O)C([O-])=O)[C@@H]1O
Safety DataBack Directory
[WGK Germany ]

3
[Storage Class]

11 - Combustible Solids
Hazard InformationBack Directory
[Uses]

Heparin disaccharide I-H sodium salt has been used as a non-naphthalene, negatively charged, bivalent compound to test its ability to induce liquid-liquid phase separation (LLPS).
[Biological Activity]

Heparin disaccharide is a bivalent compound with less hydrophobic nature. It elevates the cytosolic calcium (Ca2+) extrusion rate and may serve as a potential drug for the activation of Na+ /Ca2+ exchanger (NCX).''Products of the digestion of heparin and heparan sulfate by various heparinases
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