| Hazard Information | Back Directory | [Description]
AC410 is a potent, selective, orally-administered, small molecule inhibitor of Janus kinase 2 (JAK2, Kd = 0.18 nM) and has potential utility in autoimmune and inflammatory indications. Activity data: the specificity of AC410 for JAK2 vis-a-vis JAK1 (Kd = 2.5 nM) and JAK3 (Kd = 5 nM). | [Uses]
JAK2-IN-1 (eExample 2) is a JAK2 inhibitor, and can be used for research of proliferative disease, inflammatory disease, or renal disease[1]. | [IC 50]
JAK2 | [References]
[1] Mark W. Holladay, et al. Optically active pyrazolylaminoquinazoline, and pharmaceutical compositions and methods of use thereof. Patent. US20120053193. |
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| Company Name: |
BOC Sciences
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| Tel: |
1-631-485-4226; 16314854226 |
| Website: |
https://www.bocsci.com |
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