| Identification | Back Directory | [Name]
WS 009A | [CAS]
136286-49-2 | [Synonyms]
WS 009A
FR 901366
L-Cysteine, N-acetyl-S-(4,4a,5,6,7,12,12a,12b-octahydro-4a,8,12a,12b-tetrahydroxy-3-methyl-1,7,12-trioxobenz[a]anthracen-6a(1H)-yl)- | [Molecular Formula]
C24H25NO10S | [MDL Number]
MFCD01735938 | [MOL File]
136286-49-2.mol | [Molecular Weight]
519.52 |
| Hazard Information | Back Directory | [Description]
WS 009A is an endothelin receptor antagonist; from Streptomyces sp. No. 89009. | [Uses]
WS009A is an antagonist for endothelin receptor (ET Receptor) with IC50 of 5.8 and 6.9 μM for ET-1 receptor and ET-2 receptor. WS009A can be used in research of cardiovascular diseases[1]. | [References]
[1] Miyata S, et al., WS009 A and B, new endothelin receptor antagonists isolated from Streptomyces sp. no. 89009. I. Taxonomy, fermentation, isolation, physico-chemical properties and biological activities. J Antibiot (Tokyo). 1992 Jul;45(7):1029-40. DOI:10.7164/antibiotics.45.1029 |
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