| Identification | Back Directory | [Name]
4',5'-Didehydro-2',5'-dideoxy-2'-fluorouridine | [CAS]
1365255-75-9 | [Synonyms]
4',5'-Didehydro-2',5'-dideoxy-2'-fluorouridine
Uridine, 4',5'-didehydro-2',5'-dideoxy-2'-fluoro- | [Molecular Formula]
C9H9FN2O4 | [MDL Number]
MFCD30570262 | [MOL File]
1365255-75-9.mol | [Molecular Weight]
228.18 |
| Hazard Information | Back Directory | [Uses]
4’,5’-Didehydro-2’,5’-dideoxy-2’-fluorouridine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1]. | [References]
[1] Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88. DOI:10.2174/138161212801227005 |
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