| Identification | Back Directory | [Name]
Atrial Natriuretic Peptide (ANP) (1-28), human, porcine (Acetate) | [CAS]
1366000-58-9 | [Synonyms]
Atrial Natriuretic Peptide (ANP) (1-28), human, porcine (Acetate) | [Molecular Formula]
C129H207N45O41S3 | [MOL File]
1366000-58-9.mol | [Molecular Weight]
3140.53 |
| Chemical Properties | Back Directory | [storage temp. ]
Store at -20°C | [form ]
Solid | [color ]
White to off-white | [Water Solubility ]
25mg/ml in Water | [Sequence]
H-Ser-Leu-Arg-Arg-Ser-Ser-Cys-Phe-Gly-Gly-Arg-Met-Asp-Arg-Ile-Gly-Ala-Gln-Ser-Gly-Leu-Gly-Cys-Asn-Ser-Phe-Arg-Tyr-OH (Disulfide bridge: Cys7-Cys23) | [InChIKey]
NYSSIVMKYRVLPL-CYAMPLDWNA-N |
| Hazard Information | Back Directory | [Uses]
Carperitide acetate (Atrial Natriuretic Peptide (ANP) (1-28), human, porcine acetate) is a 28-amino acid hormone, that is normally produced and secreted by the human heart in response to cardiac injury and mechanical stretch. Carperitide acetate inhibits endothelin-1 secretion in a dose-dependent way. | [storage]
Store at -20°C | [References]
[1] Kohno M, et al. Atrial and brain natriuretic peptides inhibit the endothelin-1 secretory response to angiotensin II in porcine aorta. Circ Res. 1992 Feb;70(2):241-7. DOI:10.1161/01.res.70.2.241
[2] Kohno M, et al. Inhibition by atrial and brain natriuretic peptides of endothelin-1 secretion after stimulation with angiotensin II and thrombin of cultured human endothelial cells. J Clin Invest. 1991 Jun;87(6):1999-2004. DOI:10.1172/JCI115228
[3] Ballermann BJ, et al. Physiologic regulation of atrial natriuretic peptide receptors in rat renal glomeruli. J Clin Invest. 1985 Dec;76(6):2049-56. DOI:10.1172/JCI112207 |
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