| Identification | Back Directory | [Name]
2-Pyrazinecarboxamide, 6-fluoro-3,4-dihydro-3-oxo-, sodium salt (1:1) | [CAS]
1366418-99-6 | [Synonyms]
2-Pyrazinecarboxamide, 6-fluoro-3,4-dihydro-3-oxo-, sodium salt (1:1) | [Molecular Formula]
C5H5FN3NaO2 | [MOL File]
1366418-99-6.mol | [Molecular Weight]
181.1 |
| Hazard Information | Back Directory | [Description]
Favipiravir sodium is a selective inhibitor of viral RNA-dependent RNA polymerase with activity against many RNA viruses, influenza viruses, West Nile virus, yellow fever virus, foot-and-mouth disease virus as well as other flaviviruses, arenaviruses, bunyaviruses and alphaviruses. | [Uses]
Favipiravir (T-705) sodium is an inhibitor of viral RNA polymerase (RNA polymerase), which is converted into its active form Favipiravir-ribofuranosyl-5′-triphosphate (RTP). Favipiravir-RTP inhibits the activity of influenza virus RNA-dependent RNA polymerase (RdRP) with an IC50 of 341 nM[1][2]. | [References]
[1] Furuta Y, et al. Favipiravir (T-705), a novel viral RNA polymerase inhibitor. Antiviral Res. 2013 Nov;100(2):446-54. DOI:10.1016/j.antiviral.2013.09.015
[2] Rocha-Pereira J, et al. Favipiravir (T-705) inhibits in vitro norovirus replication. Biochem Biophys Res Commun. 2012 Aug 10;424(4):777-80. DOI:10.1016/j.bbrc.2012.07.034 |
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