ChemicalBook--->CAS DataBase List--->136675-87-1

136675-87-1

136675-87-1 Structure

136675-87-1 Structure
IdentificationBack Directory
[Name]

3',5'-Bis-O-benzoyl-2'-Deoxy-2'-fluoro-4-deoxy-arabinouridine
[CAS]

136675-87-1
[Synonyms]

3',5'-Bis-O-benzoyl-2'-Deoxy-2'-fluoro-4-deoxy-arabinouridine
1-(2'-deoxy-2'-fluoro-3',5'-dibenzoyl-D-arabinofuranosyl)pyrimidin-2(1H)-one
2(1H)-Pyrimidinone, 1-(3,5-di-O-benzoyl-2-deoxy-2-fluoro-β-D-arabinofuranosyl)-
[Molecular Formula]

C23H19FN2O6
[MOL File]

136675-87-1.mol
[Molecular Weight]

438.41
Chemical PropertiesBack Directory
[Boiling point ]

585.4±60.0 °C(Predicted)
[density ]

1.37±0.1 g/cm3(Predicted)
[pka]

1.79±0.10(Predicted)
Hazard InformationBack Directory
[Uses]

3',5'-Bis-O-benzoyl-2'-deoxy-2'-fluoro-4-deoxy-arabinouridine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].
[References]

[1] Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88. DOI:10.2174/138161212801227005
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