| Identification | Back Directory | [Name]
CLOMIPRAMINE-D3 | [CAS]
136765-29-2 | [Synonyms]
CLOMIPRAMINE-D3
[2H3]-Clomipramine
[2H3]-Clomipramine HCl
CLOMIPRAMINE-D3,100/MLINMETHANOL
5H-Dibenzb,fazepine-5-propanamine, 3-chloro-10,11-dihydro-N-methyl-N-(methyl-d3)- | [EINECS(EC#)]
604-604-1 | [Molecular Formula]
C18H19ClD3N3 | [MDL Number]
MFCD00798469 | [MOL File]
136765-29-2.mol | [Molecular Weight]
318.86 |
| Hazard Information | Back Directory | [Uses]
Clomipramine-d3 is the deuterium labeled Clomipramine. Clomipramine is a serotonin transporter (SERT), norepinephrine transporter (NET) dopamine transporter (DAT) blocker with Ki of 0.14, 54 and 3 nM, respectively[1][2]. | [References]
[1] McTavish, D. and P. Benfield, Clomipramine. An overview of its pharmacological properties and a review of its therapeutic use in obsessive compulsive disorder and panic disorder. Drugs, 1990. 39(1): p. 136-53. DOI:10.2165/00003495-199039010-00010
[2] Owens, M.J., et al., Neurotransmitter receptor and transporter binding profile of antidepressants and their metabolites. J Pharmacol Exp Ther, 1997. 283(3): p. 1305-22. PMID:9400006 |
|
| Company Name: |
Musechem
|
| Tel: |
+1-800-259-7612 |
| Website: |
www.musechem.com |
| Company Name: |
MedChemExpress
|
| Tel: |
021-58955995 |
| Website: |
www.medchemexpress.com |
|