136765-51-0

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136765-51-0 Structure

Identification	Back Directory
[Name] TEMAZEPAM-D5
[CAS] 136765-51-0
[Synonyms] TEMAZEPAM-D5 Temazepam-d5 (CRM) Temazepam-d5 solution Temazepam-d5 (phenyl-d5) TEMAZEPAM-D5,100/MLINMETHANOL [2H5]-Temazepam, racemic mixture TEMAZEPAM (D5, 98%) 100 UG/ML IN METHANOL TEMAZEPAM (D5, 98%) 1.0 MG/ML IN METHANOL Temazepam-D5Q: What is Temazepam-D5 Q: What is the CAS Number of Temazepam-D5 2H-1,4-Benzodiazepin-2-one, 7-chloro-1,3-dihydro-3-hydroxy-1-methyl-5-(phenyl-d5)- 7-chloro-3-hydroxy-1-methyl-5-(2,3,4,5,6-pentadeuteriophenyl)-3H-1,4-benzodiazepin-2-one
[EINECS(EC#)] 803-032-0
[Molecular Formula] C16H8ClD5N2O2
[MDL Number] MFCD00673311
[MOL File] 136765-51-0.mol
[Molecular Weight] 305.77

Chemical Properties	Back Directory
[Fp ] 9℃
[storage temp. ] -20°C
[InChIKey] SEQDDYPDSLOBDC-VIQYUKPQSA-N
[EPA Substance Registry System] 2H-1,4-Benzodiazepin-2-one, 7-chloro-1,3-dihydro-3-hydroxy-1-methyl-5-(phenyl-d5)- (136765-51-0)

Safety Data	Back Directory
[Hazard Codes ] F,T
[Risk Statements ] 11-23/24/25-39/23/24/25
[Safety Statements ] 7-16-36/37-45
[RIDADR ] UN1230 - class 3 - PG 2 - Methanol, solution
[WGK Germany ] 1

Hazard Information	Back Directory
[Description] Temazepam-d₅ (Item No. 15859) is an analytical reference material intended for use as an internal standard for the quantification of temazepam . Temazepam is categorized as a benzodiazepine. Temazepam has sedative-hypnotic properties and misuse via intra-arterial injection has been associated with tissue damage and subsequent amputation. Temazepam-d₅ is regulated as a Schedule IV compound in the United States. This product is intended for research and forensic applications.
[Uses] Temazepam (Phenyl D5) is labelled Temazepam (T017200) which is an intermediate-acting 3-hydroxy hypnotic of the benzodiazepine class of psychoactive drugs. Temazepam has anxiolytic (anti-anxiety), anticonvulsant, and skeletal muscle relaxant properties.
[References] [1] SHANLIN FU. Reduction of temazepam to diazepam and lorazepam to delorazepam during enzymatic hydrolysis[J]. Analytical and Bioanalytical Chemistry, 2011, 400 1: 153-164. DOI: 10.1007/s00216-011-4723-y [2] D.M. NOTT . Intra-arterial injection of temazepam in drug abusers[J]. European journal of vascular surgery, 1993, 7 1: Pages 87-89. DOI: 10.1016/s0950-821x(05)80550-x [3] GERALD FX FEENEY MB BCH BAO FRACP Harry H G M B F. Digit loss following misuse of temazepam[J]. Medical Journal of Australia, 2002, 176 8: 380. DOI: 10.5694/j.1326-5377.2002.tb04460.x

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