ChemicalBook--->CAS DataBase List--->137015-76-0

137015-76-0

137015-76-0 Structure

137015-76-0 Structure
IdentificationBack Directory
[Name]

UK 88947
[CAS]

137015-76-0
[Synonyms]

UK88
UK-88
UK 88
UK 88947
UK-88947 HCl
[Molecular Formula]

C41H63ClN6O6
[MOL File]

137015-76-0.mol
[Molecular Weight]

771.44
Hazard InformationBack Directory
[Description]

UK 88947 is a protease inhibitor.
[Uses]

UK-88947 hydrochloride is a protease inhibitor with activity in inhibiting the replication of human immunodeficiency virus HIV-1. UK-88947 hydrochloride can be added to cells before infection to block the early steps of HIV-1 replication. The use of UK-88947 hydrochloride shows its specific inhibitory effect on HIV-1. At the same time, when the virus infects cells, it inhibits the action of viral protease and affects the virus replication process[1].
[References]

[1] Antiviral activity of human immunodeficiency virus type 1 protease inhibitors in a single cycle of infection: evidence for a role of protease in the early phase DOI:10.1128/JVI.68.2.757-765.1994
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