| Identification | Back Directory | [Name]
okicenone | [CAS]
137018-54-3 | [Synonyms]
okicenone
3,4-Dihydro-4,6,9-trihydroxy-8-methylanthracen-1(2H)-one
1(2H)-Anthracenone, 3,4-dihydro-4,6,9-trihydroxy-8-methyl- | [Molecular Formula]
C15H14O4 | [MDL Number]
MFCD00906973 | [MOL File]
137018-54-3.mol | [Molecular Weight]
258.27 |
| Hazard Information | Back Directory | [Description]
Okicenone is an antibiotic, interferring with HuR RNA binding, HuR trafficking, cytokine expression and T-cell activation. | [Uses]
Okicenone is a Hu protein R (HuR) inhibitor. Okicenone inhibits HuR oligomerization, interferes with HuR RNA binding, HuR trafficking, cytokine expression and T-cell activation[1]. | [References]
[1] Meisner NC, et al. Identification and mechanistic characterization of low-molecular-weight inhibitors for HuR. Nat Chem Biol. 2007 Aug;3(8):508-15. DOI:10.1038/nchembio.2007.14 |
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