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137018-55-4

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137018-55-4 Structure

137018-55-4 Structure
IdentificationBack Directory
[Name]

U-83836E
[CAS]

137018-55-4
[Synonyms]

U 82836E
PNU-83836E
U83836E,U 83836E
(-)-2-((4-(2,6-DI-1-PYRROLIDINYL-4-PYRIMIDINYL)-1-PIPERAZINYL)METHYL)-3,4-DIHYDRO-2,3,7,8-TETRAMETHYL-2H-1-BENZOPYRAN-6-OL, 2HCL
[Molecular Formula]

C30H45ClN6O2
[MDL Number]

MFCD09750018
[MOL File]

137018-55-4.mol
[Molecular Weight]

557.18
Chemical PropertiesBack Directory
[storage temp. ]

Desiccate at -20°C
[solubility ]

Soluble in DMSO
[form ]

Solid
[color ]

Light yellow to yellow
Hazard InformationBack Directory
[Uses]

U 82836E is an iron-dependent lipid peroxidation inhibitor. This free radical scavenger has potent neuroprotective effects against ischemic injury and diabetic neuropathy.
[Biological Activity]

Free radical scavenger and antioxidant; second generation lazaroid that inhibits iron-dependent lipid peroxidation (IC 50 = 1.5 μ M). Displays neuroprotective activity in a mouse head injury model (MHI) and causes a reduction in cyanide-induced cell death in rat cortical neurons.
[storage]

Store at -20°C
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