| Identification | Back Directory | [Name]
2H-Pyrrol-2-one, 1,5-dihydro-1-[(2Z)-1-oxo-3-(3,4,5-trimethoxyphenyl)-2-propen-1-yl]- | [CAS]
1370510-16-9 | [Synonyms]
Langkamide
2H-Pyrrol-2-one, 1,5-dihydro-1-[(2Z)-1-oxo-3-(3,4,5-trimethoxyphenyl)-2-propen-1-yl]- | [Molecular Formula]
C16H17NO5 | [MOL File]
1370510-16-9.mol | [Molecular Weight]
303.31 |
| Hazard Information | Back Directory | [Uses]
Langkamide is a novel hypoxia-inducible factor-2 (HIF-2) inhibitory pyrrolidone alkaloid isolated from the roots and stems of Piper sarmentosum, which inhibits HIF-2 transcriptional activity with an EC value of 14.0μM. | [References]
[1] A new hypoxia inducible factor-2 inhibitory pyrrolinone alkaloid from roots and stems of Piper sarmentosum |
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