1370888-71-3

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1370888-71-3 Structure

Identification	Back Directory
[Name] XD14
[CAS] 1370888-71-3
[Synonyms] XD14 CS-2672 XD 14;XD-14 4-Acetyl-N-[5-[(diethylamino)sulfonyl]-2-hydroxyphenyl]-3-ethyl-5-methyl-1H-pyrrole-2-carboxamide
[Molecular Formula] C20H27N3O5S
[MDL Number] MFCD23144071
[MOL File] 1370888-71-3.mol
[Molecular Weight] 421.51

Chemical Properties	Back Directory
[density ] 1.300±0.06 g/cm3(Predicted)
[form ] Solid
[pka] 7.47±0.50(Predicted)
[color ] Off-white to light yellow

Hazard Information	Back Directory
[Uses] 4-Acetyl-N-[5-[(diethylamino)sulfonyl]-2-hydroxyphenyl]-3-ethyl-5-methyl-1H-pyrrole-2-carboxamide is a bromodomain and extra-terminal (BET) inhibitor and exerts a strong inhibitory potential on the proliferation of specific leukemia cell lines.
[IC 50] BRD2: 170 nM (Kd); BRD3: 380 nM (Kd); BRD4: 160 nM (Kd)

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