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1373154-68-7

1373154-68-7 Structure

1373154-68-7 Structure
IdentificationBack Directory
[Name]

GA3-AM
[CAS]

1373154-68-7
[Synonyms]

GA3-AM
Gibberellic Acid AcetoxyMethyl Ester
(1α,2β,4aα,4bβ,10β)-2,4a,7-Trihydroxy-1-Methyl-8-Methylenegibb-3-ene-1,10-dicarboxylic Acid 1,4a-Lactone AcetoxyMethyl Ester
(1S,2S,4aR,4bR,7S,9aS,10S,10aR)-1,2,4b,5,6,7,8,9,10,10a-Decahydro-2,7-dihydroxy-1-methyl-8-methylene-13-oxo-4a,1-(epoxymethano)-7,9a-methanobenz[a]azulene-10-acetic acid (acetyloxy)methyl ester
4a,1-(Epoxymethano)-7,9a-methanobenz[a]azulene-10-acetic acid, 1,2,4b,5,6,7,8,9,10,10a-decahydro-2,7-dihydroxy-1-methyl-8-methylene-13-oxo-, (acetyloxy)methyl ester, (1S,2S,4aR,4bR,7S,9aS,10S,10aR)-
[Molecular Formula]

C22H26O8
[MOL File]

1373154-68-7.mol
[Molecular Weight]

418.44
Chemical PropertiesBack Directory
[Melting point ]

123-126°C
[Boiling point ]

620.2±55.0 °C(Predicted)
[density ]

1.43±0.1 g/cm3(Predicted)
[storage temp. ]

-20°C Freezer
[solubility ]

Ethanol (Slightly), Methanol (Slightly), Water (Slightly, Heated, Sonicated)
[form ]

Solid
[pka]

13.26±0.70(Predicted)
[color ]

White to Off-White
Hazard InformationBack Directory
[Uses]

Gibberellic Acid Acetoxymethyl Ester is an analog of Gibberellic acid. Gibberellic acid acts as a plant growth regulator on account of its physiological and morphological effects in extremely low concentrations. Generally Gibberellic acid affects only the plant parts above the soil surface. Gibberellic acid is a hormone.
[Biological Activity]

GA3-AM is a cell permeable analog of the plant hormone gibberellic acid th at acts as a chemical dimerizer or chemical inducer of dimerization. GA3 and rapamycin chemically inducible dimerization systems are orthogonal. GA3-AM has been used in conjunction with a rapamycin dimerization system and CRISPR/Cas9 activators for temporal control of CRISPR/Cas9 activator functionenabling temporal regulation of multiple genes.
[storage]

Store at -20°C
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