| Identification | Back Directory | [Name]
ARN 077
(ARN077) | [CAS]
1373625-34-3 | [Synonyms]
URB913
ARN 077
(ARN077)
Carbamic acid, N-[(2S,3R)-2-methyl-4-oxo-3-oxetanyl]-, 5-phenylpentyl ester | [Molecular Formula]
C16H21NO4 | [MOL File]
1373625-34-3.mol | [Molecular Weight]
291.34 |
| Hazard Information | Back Directory | [Uses]
ARN 077 is a potent and selective N-acylethanolamine acid amidase (NAAA) inhibitor with an IC50 of 7 nM for human NAAA[1]. ARN 077 significantly increases palmitoyl ethanolamine (PEA) levels within the CNS and has broad antinociceptive activity in mice and rats[2]. | [storage]
Store at -20°C | [References]
[1] Sasso O, et al. Antinociceptive effects of the N-acylethanolamine acid amidase inhibitor ARN077 in rodent pain models. Pain. 2013 Mar;154(3):350-60. DOI:10.1016/j.pain.2012.10.018
[2] Davis MP, et al. Cannabinoids in pain management: CB1, CB2 and non-classic receptor ligands. Expert Opin Investig Drugs. 2014 Aug;23(8):1123-40. DOI:10.1517/13543784.2014.918603 |
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| Company Name: |
MedChemExpress
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| Tel: |
021-58955995 |
| Website: |
www.medchemexpress.com |
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