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1374226-74-0

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1374226-74-0 Structure

1374226-74-0 Structure
IdentificationBack Directory
[Name]

N-(3R)-1-Azabicyclo[2.2.2]oct-3-yl-5,6,7,8-tetrahydro-1-naphthalenecarboxamide
[CAS]

1374226-74-0
[Synonyms]

Palonosetron Impurity 21
(R)-N-(quinuclidin-3-yl)-5,6,7,8-tetrahydronaphthalene-1-carboxamide
N-(3R)-1-Azabicyclo[2.2.2]oct-3-yl-5,6,7,8-tetrahydro-1-naphthalenecarboxamide
1-Naphthalenecarboxamide, N-(3R)-1-azabicyclo[2.2.2]oct-3-yl-5,6,7,8-tetrahydro-
N-[(2R)-4-azabicyclo[2.2.2]octan-2-yl]-5,6,7,8-tetrahydronaphthalene-1-carboxamide
[Molecular Formula]

C18H24N2O
[MOL File]

1374226-74-0.mol
[Molecular Weight]

284.4
Chemical PropertiesBack Directory
[Melting point ]

157-159oC
[storage temp. ]

Refrigerator
[solubility ]

Chloroform (Slightly), DMSO (Slightly), Methanol (Slightly)
[form ]

Solid
[color ]

Pale Beige
Hazard InformationBack Directory
[Uses]

N-(3R)-1-Azabicyclo[2.2.2]oct-3-yl-5,6,7,8-tetrahydro-1-naphthalenecarboxamide is an intermediate in the synthesis of Palonosteron (P165805), an serotonin 5-HT3 receptor antagonist used in the prevention and treatment of chemotherapy-induced nausea and vomiting.
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