| Identification | Back Directory | [Name]
4-Pyridinecarboxylic acid, (2E)-2-(8-hydroxy-3-methyl-4-oxo-1(4H)-naphthalenylidene)hydrazide | [CAS]
1374305-45-9 | [Synonyms]
Antiproliferative agent-22
4-Pyridinecarboxylic acid, (2E)-2-(8-hydroxy-3-methyl-4-oxo-1(4H)-naphthalenylidene)hydrazide | [Molecular Formula]
C17H13N3O3 | [MOL File]
1374305-45-9.mol | [Molecular Weight]
307.3 |
| Hazard Information | Back Directory | [Uses]
Antiproliferative agent-22 (compound 2) is an anticancer agent. Antiproliferative agent-22 shoes anti-proliferative activities against MCF-7, MDA-MB-231 and MDA-MB-468 cells with IC50 values of 6.2 μM, 3.3 μM and 3.3 μM, respectively[1]. | [References]
[1] Prasad Dandawate, et al. Synthesis, characterization, molecular docking and cytotoxic activity of novel plumbagin hydrazones against breast cancer cells. Bioorg Med Chem Lett. 2012 May 1;22(9):3104-8. DOI:10.1016/j.bmcl.2012.03.060 |
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