| Identification | Back Directory | [Name]
2-(4-METHYLPHENOXY)-N-(1H-PYRAZOL-3-YL)-N-(THIOPHEN-2-YLMETHYL)ACETAMIDE | [CAS]
1374760-95-8 | [Synonyms]
FEMA4809
FEMA-4809
FEMA 4809
Acetamide, 2-(4-methylphenoxy)-N-1H-pyrazol-3-yl-N-(2-thienylmethyl)-
2-(4-METHYLPHENOXY)-N-(1H-PYRAZOL-3-YL)-N-(THIOPHEN-2-YLMETHYL)ACETAMIDE | [EINECS(EC#)]
815-961-9 | [Molecular Formula]
C17H17N3O2S | [MOL File]
1374760-95-8.mol | [Molecular Weight]
327.4 |
| Hazard Information | Back Directory | [Uses]
FEMA 4809 is a TRPM8 receptor agonist (EC50=0.2 nM) for use as a cooling agent. TRPM8 is the ion channel responsible for the cool perception[1]. | [References]
[1] Alain Noncovich, et al. Discovery and development of a novel class of phenoxyacetyl amides as highly potent TRPM8 agonists for use as cooling agents. Bioorg Med Chem Lett. 2017 Aug 15;27(16):3931-3938. DOI:10.1016/j.bmcl.2017.04.003 |
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