| Identification | Back Directory | [Name]
Baringolin | [CAS]
1374772-61-8 | [Synonyms]
Kocurin
Baringolin
Alaninamide, N-[[(4R)-2-[(1S)-1-[[[2-[(1S)-1,3-diamino-3-oxopropyl]-4-thiazolyl]carbonyl]amino]-2-phenylethyl]-4,5-dihydro-4-thiazolyl]carbonyl]-L-tyrosyl-2-[5-(4-carboxy-5-methyl-2-oxazolyl)-6-[2'-(2S)-2-pyrrolidinyl[2,4'-bithiazol]-4-yl]-2-pyridinyl]-4-thiazolecarbonyl-2,3-didehydroalanyl-L-alanyl... | [Molecular Formula]
C69H66N18O13S5 | [MOL File]
1374772-61-8.mol | [Molecular Weight]
1515.7 |
| Hazard Information | Back Directory | [Uses]
Baringolin is a thiopeptide antibiotic from Kocuria palustris. Baringolin is effective against methicillin-?resistant Staphylococcus aureus. | [in vivo]
Kocurin (1.25-10 mg/kg; intravenous injection; single dose) has the 100% effective dose (ED100) values of 2.5 and 5.0 mg/kg for MRSA, and an ED100 value of 10.0 mg/kg for VRE in the BALB/c mouse septicemia model[1]. |
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