| Identification | Back Directory | [Name]
Benzamide, 5-chloro-N-[5-(4-chlorophenyl)-1,3,4-thiadiazol-2-yl]-2-hydroxy- | [CAS]
1374959-91-7 | [Synonyms]
FAK-IN-8 Benzamide, 5-chloro-N-[5-(4-chlorophenyl)-1,3,4-thiadiazol-2-yl]-2-hydroxy- | [Molecular Formula]
C15H9Cl2N3O2S | [MOL File]
1374959-91-7.mol | [Molecular Weight]
366.22 |
| Hazard Information | Back Directory | [Uses]
FAK-IN-8 (compound 5h) is a FAK inhibitor (IC50=5.32 μM). FAK-IN-8 has good anti-proliferative activity and can be used in cancer research[1]. | [IC 50]
FAK: 5.32 μM (IC50) | [References]
[1] Yang XH, et al. Synthesis, biological evaluation, and molecular docking studies of 1,3,4-thiadiazol-2-amide derivatives as novel anticancer agents. Bioorg Med Chem. 2012 May 1;20(9):2789-95. DOI:10.1016/j.bmc.2012.03.040 |
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