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1374959-91-7

1374959-91-7 Structure

1374959-91-7 Structure
IdentificationBack Directory
[Name]

Benzamide, 5-chloro-N-[5-(4-chlorophenyl)-1,3,4-thiadiazol-2-yl]-2-hydroxy-
[CAS]

1374959-91-7
[Synonyms]

FAK-IN-8
Benzamide, 5-chloro-N-[5-(4-chlorophenyl)-1,3,4-thiadiazol-2-yl]-2-hydroxy-
[Molecular Formula]

C15H9Cl2N3O2S
[MOL File]

1374959-91-7.mol
[Molecular Weight]

366.22
Chemical PropertiesBack Directory
[density ]

1.579±0.06 g/cm3(Predicted)
[pka]

6.92±0.50(Predicted)
Hazard InformationBack Directory
[Uses]

FAK-IN-8 (compound 5h) is a FAK inhibitor (IC50=5.32 μM). FAK-IN-8 has good anti-proliferative activity and can be used in cancer research[1].
[IC 50]

FAK: 5.32 μM (IC50)
[References]

[1] Yang XH, et al. Synthesis, biological evaluation, and molecular docking studies of 1,3,4-thiadiazol-2-amide derivatives as novel anticancer agents. Bioorg Med Chem. 2012 May 1;20(9):2789-95. DOI:10.1016/j.bmc.2012.03.040
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Company Name: Shanghai Beckham Medical Technology Co., Ltd  
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