| Identification | Back Directory | [Name]
eurystatin A | [CAS]
137563-63-4 | [Synonyms]
eurystatin A
L-Leucine, N2-[(2E)-6-methyl-1-oxo-2-hepten-1-yl]-L-ornithyl-(3S)-3-amino-2-oxobutanoyl-, (3→1)-lactam | [Molecular Formula]
C23H38N4O5 | [MOL File]
137563-63-4.mol | [Molecular Weight]
450.576 |
| Chemical Properties | Back Directory | [Melting point ]
291-294 °C(Solv: acetonitrile (75-05-8); water (7732-18-5)) | [density ]
1.13±0.1 g/cm3(Predicted) | [pka]
10.53±0.70(Predicted) |
| Hazard Information | Back Directory | [Uses]
Eurystatin A is a prolyl endopeptidase inhibitor, L-Leucine and L-Ornithine are the direct precursors of the L-Leucine and L-Ornithine moieties of eurystatins A[1]. | [References]
[1] K Suzuki, et al. Eurystatins A and B, new prolyl endopeptidase inhibitors. III. Fermentation and controlled biosynthesis of eurystatin analogs by Streptomyces eurythermus. J Antibiot (Tokyo). 1994 Sep;47(9):982-91. DOI:10.7164/antibiotics.47.982 |
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