ChemicalBook--->CAS DataBase List--->1378524-41-4

1378524-41-4

1378524-41-4 Structure

1378524-41-4 Structure
IdentificationBack Directory
[Name]

VUF11207
[CAS]

1378524-41-4
[Synonyms]

VUF11207
VUF11207 Triflate
VUF11207 TFA salt
VUF11207;VUF-11207;VUF 11207
VUF11207 trifluoroacetate salt
(E)-N-(3-(2-Fluorophenyl)-2-methylallyl)-3,4,5-trimethoxy-N-(2-(1-methylpyrrolidin-2-yl)ethyl)
(E)-N-(3-(2-fluorophenyl)-2-Methylallyl)-3,4,5-triMethoxy-N-(2-(1-Methylpyrrolidin-2-yl)ethyl)benzaMide
(E)-N-(3-(2-Fluorophenyl)-2-methylallyl)-3,4,5-trimethoxy-N-(2-(1-methylpyrrolidin-2-yl)ethyl)benzamide trifluoroacetate salt
N-[(2E)-3-(2-Fluorophenyl)-2-methyl-2-propen-1-yl]-3,4,5-trimethoxy-N-[2-(1-methyl-2-pyrrolidinyl)ethyl]-benzamide trifluoroacetate salt
[Molecular Formula]

C27H35FN2O4
[MDL Number]

MFCD23136023
[MOL File]

1378524-41-4.mol
[Molecular Weight]

470.58
Chemical PropertiesBack Directory
[Boiling point ]

615.9±55.0 °C(Predicted)
[density ]

1.134±0.06 g/cm3(Predicted)
[storage temp. ]

-20°C
[solubility ]

H2O: soluble5mg/mL, clear (warmed)
[form ]

oil
[pka]

10.26±0.40(Predicted)
[color ]

white to beige
[Water Solubility ]

H2O: 5mg/mL, clear (warmed)
Safety DataBack Directory
[Symbol(GHS) ]


GHS07
[Signal word ]

Warning
[Hazard statements ]

H302-H315-H319-H335
[Precautionary statements ]

P261-P305+P351+P338
[WGK Germany ]

3
Hazard InformationBack Directory
[Biological Activity]

VUF11207 is a highly potent CXCR7 agonist. VUF11207 induces recruitment of β-arrestin2 to the CXCR7 followed by internalization of the receptor.''VUF11207 is considered as a selective inhibitor of CXCR4 (C-X-C motif chemokine receptor 4).
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