| Identification | Back Directory | [Name]
CPI-268456 | [CAS]
1380087-86-4 | [Synonyms]
CPI-268456
CPI 268456;CPI268456
4H-Isoxazolo[5,4-d][2]benzazepine-4-acetamide, 8-chloro-6-(4-chlorophenyl)-1-methyl-, (4S)-
2-((4R)-8-chloro-6-(4-chlorophenyl)-1-methyl-4H-benzo[c]isoxazolo[4,5-e]azepin-4-yl)acetamide | [EINECS(EC#)]
604-604-1 | [Molecular Formula]
C20H15Cl2N3O2 | [MDL Number]
MFCD28987428 | [MOL File]
1380087-86-4.mol | [Molecular Weight]
400.258 |
| Chemical Properties | Back Directory | [Boiling point ]
649.8±55.0 °C(Predicted) | [density ]
1.49±0.1 g/cm3(Predicted) | [storage temp. ]
Store at -20°C | [solubility ]
DMF: 30 mg/ml; DMF:PBS (pH 7.2) (1:3): 0.25 mg/ml; DMSO: 20 mg/ml; Ethanol: 20 mg/ml | [form ]
A crystalline solid | [pka]
16.03±0.40(Predicted) |
| Hazard Information | Back Directory | [Uses]
BRD4-IN-3 (compound 141) is a potent BRD4 inhibitor with an IC50 of <0.5 μM. BRD4-IN-3 shows cytoxicity for MYC-Raji with an IC50 value of >1 μM[1]. | [IC 50]
BRD4: <0.5 μM (IC50) | [References]
[1] Brian K. Albrecht, et al. Bromodomain inhibitors and uses thereof. WO2012075383A2. |
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Twochem Co.Ltd
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021-021-58111628 15800915896 |
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www.twochem.com |
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