| Identification | Back Directory | [Name]
5-[3-(Aarboxymethoxy)phenyl]-3-(4,5-dimethyl-2-thiazolyl)-2-(4-sulfophenyl)-2H-tetrazolium inner salt | [CAS]
138169-43-4 | [Synonyms]
MC MTS(dye) FEMA 2696 METOLOSE(R) METHYLCEL MC METHOCEL(R) MC METHYLCELLULOSUM METHOCEL(R) 60 HG METHOCEL(R) 65 HG METHOCEL(R) 90 HG 'TYLOSE'(R) MH 300 MODIFIED CELLULOSE 'TYLOSE'(R) MH 1000 METHYL CELLULOSE 50 METHYL CELLULOSE 15 METHYL CELLULOSE 25 METHYL CELLULOSE 400 METHYL CELLULOSE 100 METHYL CELLULOSE 1500 METHYL CELLULOSE 4,000 METHYL CELLULOSE NO 15 MODIFIED CELLULOSE, MC CELLULOSE METHYL ETHER METHYL CELLULOSE NO 400 METHYL CELLULOSE NO 100 METHYL CELLULOSE NO 1500 METHYL CELLULOSE 400 CPS METHYL CELLULOSE NO 4000 METHYL CELLULOSE 4000 CPS METHYL CELLULOSE METHOCEL A4C MTS Reagent, cell proliferation assay reagent 3-(4,5-dimethylthiazol-2-yl)-5-(3-carboxymethoxyphenyl)-2-(4-sulfophenyl)-2H-tetrazolium 5-[3-(Aarboxymethoxy)phenyl]-3-(4,5-dimethyl-2-thiazolyl)-2-(4-sulfophenyl)-2H-tetrazolium inner salt 5-[3-(Carboxymethoxy)phenyl]-3-(4,5-dimethyl-2-thiazolyl)-2-(4-sulfophenyl)-2H-tetrazolium inner salt 2H-TetrazoliuM,5-[3-(carboxyMethoxy)phenyl]-3-(4,5-diMethyl-2-thiazolyl)-2-(4-sulfophenyl)-,inner salt 4-{5-[3-(Carboxymethoxy)phenyl]-3-(4,5-dimethyl-1,3-thiazol-2-yl)-2H-tetrazol-3-ium-2-yl}benzenesulfonate | [EINECS(EC#)]
232-674-9 | [Molecular Formula]
C20H17N5O6S2 | [MDL Number]
MFCD00081763 | [MOL File]
138169-43-4.mol | [Molecular Weight]
487.515 |
| Chemical Properties | Back Directory | [form ]
powder
| [InChIKey]
APRZHQXAAWPYHS-UHFFFAOYSA-N | [SMILES]
[N+]1(=NC(C2=CC=CC(OCC(=O)O)=C2)=NN1C1=CC=C(S([O-])(=O)=O)C=C1)C1SC(C)=C(C)N=1 |
| Hazard Information | Back Directory | [Description]
MTS reagent is one of the most common water-soluble tetrazolium reagents that are widely used to quantify cell viability by absorption spectrophotometry. A variety of tetrazolium inner salts are used for determining cell viability in proliferation assays by monitoring their color changes. Metabolically active cells reduce colorless tetrazolium inner salts into the colored formazan products that might be either soluble or insoluble in cell culture media depending on the structures of tetrazolium reagents. The conversion of tetrazolium inner salts to formazans is thought to be carried out by NAD(P)H-dependent dehydrogenase enzymes. | [Biological Activity]
Tetrazolium inner salt used for determining cell viability in proliferation assays. Reduced in metabolically active cells to a colored formazan product that is soluble in cell culture media. This conversion is thought to be carried out by NAD(P)H-dependent dehydrogenase enzymes. | [References]
[1] MORVA MANSOURY. The edge effect: A global problem. The trouble with culturing cells in 96-well plates[J]. Biochemistry and Biophysics Reports, 2021, 26: Article 100987. DOI:10.1016/j.bbrep.2021.100987. [2] VICTOR AKPE. Profiling the Neoplasm Microenvironment of Silica Nanomaterial-Derived Scaffolds of Single, 2-, and 3-Composite Systems.[J]. Assay and drug development technologies, 2021, 19 3: 191-203. DOI:10.1089/adt.2020.1020. [3] YUTANG WANG. A Modified MTS Proliferation Assay for Suspended Cells to Avoid the Interference by Hydralazine and β-Mercaptoethanol.[J]. Assay and drug development technologies, 2021, 19 3: 184-190. DOI:10.1089/adt.2020.1027. |
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Synchem OHG
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+49 5662 408730 |
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www.synchem.de |
| Company Name: |
Rhawn Reagent
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400-400-1332688 18019345275 |
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http://www.rhawn.cn |
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