ChemicalBook--->CAS DataBase List--->138169-43-4

138169-43-4

138169-43-4 Structure

138169-43-4 Structure
IdentificationBack Directory
[Name]

5-[3-(Aarboxymethoxy)phenyl]-3-(4,5-dimethyl-2-thiazolyl)-2-(4-sulfophenyl)-2H-tetrazolium inner salt
[CAS]

138169-43-4
[Synonyms]

MC
MTS(dye)
FEMA 2696
METOLOSE(R)
METHYLCEL MC
METHOCEL(R) MC
METHYLCELLULOSUM
METHOCEL(R) 60 HG
METHOCEL(R) 65 HG
METHOCEL(R) 90 HG
'TYLOSE'(R) MH 300
MODIFIED CELLULOSE
'TYLOSE'(R) MH 1000
METHYL CELLULOSE 50
METHYL CELLULOSE 15
METHYL CELLULOSE 25
METHYL CELLULOSE 400
METHYL CELLULOSE 100
METHYL CELLULOSE 1500
METHYL CELLULOSE 4,000
METHYL CELLULOSE NO 15
MODIFIED CELLULOSE, MC
CELLULOSE METHYL ETHER
METHYL CELLULOSE NO 400
METHYL CELLULOSE NO 100
METHYL CELLULOSE NO 1500
METHYL CELLULOSE 400 CPS
METHYL CELLULOSE NO 4000
METHYL CELLULOSE 4000 CPS
METHYL CELLULOSE METHOCEL A4C
MTS Reagent, cell proliferation assay reagent
3-(4,5-dimethylthiazol-2-yl)-5-(3-carboxymethoxyphenyl)-2-(4-sulfophenyl)-2H-tetrazolium
5-[3-(Aarboxymethoxy)phenyl]-3-(4,5-dimethyl-2-thiazolyl)-2-(4-sulfophenyl)-2H-tetrazolium inner salt
5-[3-(Carboxymethoxy)phenyl]-3-(4,5-dimethyl-2-thiazolyl)-2-(4-sulfophenyl)-2H-tetrazolium inner salt
2H-TetrazoliuM,5-[3-(carboxyMethoxy)phenyl]-3-(4,5-diMethyl-2-thiazolyl)-2-(4-sulfophenyl)-,inner salt
4-{5-[3-(Carboxymethoxy)phenyl]-3-(4,5-dimethyl-1,3-thiazol-2-yl)-2H-tetrazol-3-ium-2-yl}benzenesulfonate
[EINECS(EC#)]

232-674-9
[Molecular Formula]

C20H17N5O6S2
[MDL Number]

MFCD00081763
[MOL File]

138169-43-4.mol
[Molecular Weight]

487.515
Chemical PropertiesBack Directory
[form ]

powder
[InChIKey]

APRZHQXAAWPYHS-UHFFFAOYSA-N
[SMILES]

[N+]1(=NC(C2=CC=CC(OCC(=O)O)=C2)=NN1C1=CC=C(S([O-])(=O)=O)C=C1)C1SC(C)=C(C)N=1
Safety DataBack Directory
[Safety Statements ]

24/25
[WGK Germany ]

3
[RTECS ]

FJ5959000
[F ]

3
Hazard InformationBack Directory
[Description]

MTS reagent is one of the most common water-soluble tetrazolium reagents that are widely used to quantify cell viability by absorption spectrophotometry. A variety of tetrazolium inner salts are used for determining cell viability in proliferation assays by monitoring their color changes. Metabolically active cells reduce colorless tetrazolium inner salts into the colored formazan products that might be either soluble or insoluble in cell culture media depending on the structures of tetrazolium reagents. The conversion of tetrazolium inner salts to formazans is thought to be carried out by NAD(P)H-dependent dehydrogenase enzymes.
[Biological Activity]

Tetrazolium inner salt used for determining cell viability in proliferation assays. Reduced in metabolically active cells to a colored formazan product that is soluble in cell culture media. This conversion is thought to be carried out by NAD(P)H-dependent dehydrogenase enzymes.
[References]

[1] MORVA MANSOURY. The edge effect: A global problem. The trouble with culturing cells in 96-well plates[J]. Biochemistry and Biophysics Reports, 2021, 26: Article 100987. DOI:10.1016/j.bbrep.2021.100987.
[2] VICTOR AKPE. Profiling the Neoplasm Microenvironment of Silica Nanomaterial-Derived Scaffolds of Single, 2-, and 3-Composite Systems.[J]. Assay and drug development technologies, 2021, 19 3: 191-203. DOI:10.1089/adt.2020.1020.
[3] YUTANG WANG. A Modified MTS Proliferation Assay for Suspended Cells to Avoid the Interference by Hydralazine and β-Mercaptoethanol.[J]. Assay and drug development technologies, 2021, 19 3: 184-190. DOI:10.1089/adt.2020.1027.
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