ChemicalBook--->CAS DataBase List--->1384864-80-5

1384864-80-5

Request For Quotation
1384864-80-5 Structure

1384864-80-5 Structure
IdentificationBack Directory
[Name]

NCGC00249987
[CAS]

1384864-80-5
[Synonyms]

NCGC00249987
[Molecular Formula]

C16H11FN4O2S
[MDL Number]

MFCD32878251
[MOL File]

1384864-80-5.mol
[Molecular Weight]

342.35
Chemical PropertiesBack Directory
[density ]

1.39±0.1 g/cm3(Predicted)
[form ]

Solid
[pka]

11.32±0.46(Predicted)
[color ]

Off-white to light yellow
Hazard InformationBack Directory
[Uses]

NCGC00249987 is a highly selective and allosteric Tyr phosphatase activity of Eya2 inhibitor with IC50s of 3 μM and 6.9 μM for Eya2 ED and MBP-Eya2 FL. NCGC00249987 specifically targets migration, invadopodia formation, and invasion of lung cancer cells[1].
[References]

[1] Anantharajan J, et al. Structural and Functional Analyses of an Allosteric EYA2 Phosphatase Inhibitor That Has On-Target Effects in Human Lung Cancer Cells. Mol Cancer Ther. 2019 Sep;18(9):1484-1496. DOI:10.1158/1535-7163.MCT-18-1239
1384864-80-5 suppliers list
Company Name: TargetMol Chemicals Inc.
Tel: +1-781-999-5354; +17819995354 , +17819995354
Website: https://www.targetmol.com/
Company Name: TargetMol Chemicals Inc.
Tel: +1-781-999-5354;
Website: https://www.targetmol.com/
Company Name: Aladdin Scientific
Tel:
Website: www.aladdinsci.com/
Company Name: TargetMol Chemicals Inc.
Tel: +17819995354 , +17819995354
Website:
Company Name: Shanghai Beckham Medical Technology Co., Ltd  
Tel: 13816613772
Website: www.chemicalbook.com/ShowSupplierProductsList16976/0_EN.htm
Company Name: Shanghai EFE Biological Technology Co., Ltd.  
Tel: 021-65675885 18964387627
Website: http://www.efebio.com
Company Name: Beijing Jin Ming Biotechnology Co., Ltd.  
Tel: 010-60605840 15801484223;
Website: http://www.jm-bio.com/
Company Name: TargetMol Chemicals Inc.  
Tel: 4008200310
Website: https://www.targetmol.cn/
Company Name: RD International Technology Co., Limited  
Tel: 18024082417
Website: www.ruidiresearch.com
Company Name: MedChemExpress  
Tel: 021-58955995
Website: www.medchemexpress.com
Tags:1384864-80-5 Related Product Information