| Identification | Back Directory | [Name]
9-Hydroxycanthin-6-one | [CAS]
138544-91-9 | [Synonyms]
9-Hydroxycanthin-6-one
9-Hydroxy-6H-indolo[3,2,1-de][1,5]naphthyridin-6-one
6H-Indolo[3,2,1-de][1,5]naphthyridin-6-one, 9-hydroxy- | [Molecular Formula]
C14H8N2O2 | [MDL Number]
MFCD21333396 | [MOL File]
138544-91-9.mol | [Molecular Weight]
236.23 |
| Hazard Information | Back Directory | [Uses]
9-Hydroxycanthin-6-one is an alkaloid compound. 9,10-Dimethoxycanthin-6-one exhibits NF-κB inhibitory effects with an IC50 of 3.8 μM[1]. | [Definition]
ChEBI: An indole alkaloid that is canthin-6-one substituted by a hydroxy group at position 9. Isolated from the roots of Eurycoma longifolia, it exhibits antineoplastic activity. | [References]
[1] Thi Van Anh Tran, et al. NF-κB inhibitors from Eurycoma longifolia. J Nat Prod. 2014 Mar 28;77(3):483-8. DOI:10.1021/np400701k |
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