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138544-91-9

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138544-91-9 Structure

138544-91-9 Structure
IdentificationBack Directory
[Name]

9-Hydroxycanthin-6-one
[CAS]

138544-91-9
[Synonyms]

9-Hydroxycanthin-6-one
9-Hydroxy-6H-indolo[3,2,1-de][1,5]naphthyridin-6-one
6H-Indolo[3,2,1-de][1,5]naphthyridin-6-one, 9-hydroxy-
[Molecular Formula]

C14H8N2O2
[MDL Number]

MFCD21333396
[MOL File]

138544-91-9.mol
[Molecular Weight]

236.23
Chemical PropertiesBack Directory
[Boiling point ]

410.1±45.0 °C(Predicted)
[density ]

1.53±0.1 g/cm3(Predicted)
[pka]

8.86±0.20(Predicted)
Hazard InformationBack Directory
[Uses]

9-Hydroxycanthin-6-one is an alkaloid compound. 9,10-Dimethoxycanthin-6-one exhibits NF-κB inhibitory effects with an IC50 of 3.8 μM[1].
[Definition]

ChEBI: An indole alkaloid that is canthin-6-one substituted by a hydroxy group at position 9. Isolated from the roots of Eurycoma longifolia, it exhibits antineoplastic activity.
[References]

[1] Thi Van Anh Tran, et al. NF-κB inhibitors from Eurycoma longifolia. J Nat Prod. 2014 Mar 28;77(3):483-8. DOI:10.1021/np400701k
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