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1386980-04-6

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1386980-04-6 Structure

1386980-04-6 Structure
IdentificationBack Directory
[Name]

DYRKs-IN-2
[CAS]

1386980-04-6
[Synonyms]

DYRKs-IN-2
DYRKs IN 2,DYRKsIN2
Pyrido[2,3-d]pyrimidine-6-carboxamide, N-[5-[[(3-amino-1-phenylpropyl)amino]carbonyl]-2-chlorophenyl]-7,8-dihydro-2-[[3-(4-methyl-1-piperazinyl)propyl]amino]-7-oxo-
[Molecular Formula]

C32H38ClN9O3
[MDL Number]

MFCD32215331
[MOL File]

1386980-04-6.mol
[Molecular Weight]

632.16
Chemical PropertiesBack Directory
[density ]

1.40±0.1 g/cm3(Predicted)
[pka]

10.84±0.70(Predicted)
Hazard InformationBack Directory
[Uses]

DYRKs-IN-2 (Example 132) is a potent DYRKs inhibitor with IC50s of 30.6 nM and 12.8 nM for DYRK1B and DYRK1A, respectively. DYRKs-IN-2 has antitumor activity[1].
[References]

[1] Kevin Anderson, et al. Pyrido pyrimidines. US20120184542A1
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Company Name: TargetMol Chemicals Inc.
Tel: +1-781-999-5354;
Website: https://www.targetmol.com/
Company Name: TargetMol Chemicals Inc.
Tel: +17819995354 , +17819995354
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