| Identification | Back Directory | [Name]
(-)-4-(2-Chlorobenzyl)-5-oxo-4-phenylhexanoic acid | [CAS]
13878-10-9 | [Synonyms]
Caprochlorone
(-)-4-(2-Chlorobenzyl)-5-oxo-4-phenylhexanoic acid
Benzenepentanoic acid, γ-acetyl-2-chloro-γ-phenyl-, (-)- | [Molecular Formula]
C19H19ClO3 | [MOL File]
13878-10-9.mol | [Molecular Weight]
330.81 |
| Hazard Information | Back Directory | [Uses]
Caprochlorone has antiviral activity against orthopoxvirus. Caprochlorone can inhibit cell penetration by virus, also delays release of newly formed virus from the cell. Caprochlorone decreases the titers of influenza virus in infected-mice lungs[1][2][3]. | [References]
[1] Smee DF, Sidwell RW. A review of compounds exhibiting anti-orthopoxvirus activity in animal models. Antiviral Res. 2003;57(1-2):41-52. DOI:10.1016/s0166-3542(02)00199-7
[2] Stanfield FJ, Haff RF, Stewart RC. The antiviral activity of caprochlorone. Proc Soc Exp Biol Med. 1967;125(1):297-303. DOI:10.3181/00379727-125-32076
[3] LIU OC, et al. Studies on the chemotherapy of viral infections. II. The effect of caprochlorone on influenza virus infections in mice. J Immunol. 1957;78(3):222-227. PMID:13429090 |
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