| Identification | Back Directory | [Name]
2-[(4-PHENYLPIPERAZIN-1-YL)METHYL]-2,3-DIHYDROIMIDAZO[1,2-C]QUINAZOLIN-5(6H)-ONE | [CAS]
139047-55-5 | [Synonyms]
2-PMDQ
3-MPPI
2-[(4-PHENYLPIPERAZIN-1-YL)METHYL]-2,3-DIHYDROIMIDAZO[1,2-C]QUINAZOLIN-5(6H)-ONE
Imidazo[1,2-c]quinazolin-5(3H)-one, 2,6-dihydro-2-[(4-phenyl-1-piperazinyl)methyl]- | [Molecular Formula]
C21H23N5O | [MDL Number]
MFCD00673885 | [MOL File]
139047-55-5.mol | [Molecular Weight]
361.44 |
| Hazard Information | Back Directory | [Uses]
2-PMDQ is an analog of Ketanserin with beneficial hemodynamic effects in portal hypertensive rats. Anti-hypertensive effects. | [Definition]
ChEBI: 2-[(4-phenyl-1-piperazinyl)methyl]-3,6-dihydro-2H-imidazo[1,2-c]quinazolin-5-one is a member of piperazines. | [Biological Activity]
Very potent ligand for α 1 sites (K i for displacement of prazosin = 0.2 nM). Also binds to 5-HT 1A sites (K i = 50 nM). |
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BOC Sciences
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