| Identification | Back Directory | [Name]
TYRPHOSTIN B48 | [CAS]
139087-53-9 | [Synonyms]
AG 494
TYRPHOSTIN B48
TYRPHOSTIN AG 494
A-CYANO-(3,4-DIHYDROXY)-N-PHENYLCINNAMIDE
A-CYANO-(3,4-DIHYDROXY)-N-PHENYLCINNAMAMIDE
ALPHA-CYANO-(3,4-DIHYDROXY)-N-PHENYLCINNAMIDE
N-PHENYL-3,4-DIHYDROXYBENZYLIDENECYANOACETAMIDE
2-Propenamide, 2-cyano-3-(3,4-dihydroxyphenyl)-N-phenyl-
(E)-2-CYANO-3-(3,4-DIHYDROXYPHENYL)-N-PHENYL-2-PROPENAMIDE | [Molecular Formula]
C16H12N2O3 | [MDL Number]
MFCD00209863 | [MOL File]
139087-53-9.mol | [Molecular Weight]
280.28 |
| Chemical Properties | Back Directory | [Boiling point ]
586.9±50.0 °C(Predicted) | [density ]
1.416±0.06 g/cm3(Predicted) | [storage temp. ]
−20°C | [solubility ]
DMSO: soluble | [pka]
8.80±0.35(Predicted) |
| Hazard Information | Back Directory | [Uses]
AG 494 is a potent inhibitor of epidermal growth factor receptor (EGF-R). AG 494 has been found to inhibit cell growth even past the restriction point when receptor activation is no longer necessary; in particular AG 494 causes cells to arrest at late G1 and and during S phase. |
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| Company Name: |
BOC Sciences
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| Tel: |
16314854226 |
| Website: |
www.bocsci.com |
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